How precision health actually works.
MetaQon runs on Precisya's precision-health intelligence, built on 25M+ peer-reviewed publications. Every risk it surfaces traces back to that published evidence. Nothing is invented, and nothing is guessed.
We retrieve evidence. We don't generate it.
MetaQon's interpretations, powered by Precisya, are anchored in a corpus of 25M+ peer-reviewed scientific publications. When your genetic markers and biomarkers are analyzed, every association drawn is one the published literature already supports. That could be a link between a variant and a risk, or between a biomarker and a condition. If the evidence isn't there, the claim isn't made.
Peer-reviewed only
We draw on published, peer-reviewed research. Not anecdote or opinion, and not marketing.
Traceable
Each interpretation can be traced back to the studies behind it. The published evidence is the source of record.
Updated as science moves
The evidence base keeps growing, and our interpretations move with it as the literature advances.
Nothing here is invented or guessed at. It's grounded in the published record.
From your data to a grounded conclusion.
This is the genetic testing science behind the report: a chain of evidence rather than a black box. At a high level, it runs in four steps.
Read the markers
We analyze your genetic markers and your diagnostic biomarkers. These are the measurable signals from your DNA and your bloodwork.
Match to the literature
Each marker is mapped to the published findings that describe what it means: its association with risk, its clinical significance, and the caveats that come with it.
Weight for you
Findings are then weighted for relevance, taking ancestry and regional disease prevalence into account. The interpretation reflects your biology rather than a population average drawn from elsewhere. This is where polygenic risk is scored for your context.
Resolve into risk
The weighted evidence resolves into a clear, sourced picture of predisposition and current state. It's explained in plain language and stays traceable to its source.
Genetic markers tell us what's possible and biomarkers tell us what's happening now. It's the published literature that lets us say what either one actually means for you.
Most genomics wasn't built for diverse ancestries.
Most of the world's genomic research has been conducted on people of European ancestry. Risk models built on that data can misread more diverse bodies. A variant that means one thing in a European cohort can carry different weight, or a different prevalence, in ours. Applied without care, the science meant to personalize your health can quietly get you wrong.
MetaQon is calibrated for the people we serve.
Multi-ancestry reference panels
We interpret against reference data that includes diverse, under-represented populations, rather than a single-ancestry baseline borrowed from elsewhere.
Regional disease prevalence weighting
Interpretations are weighted by how conditions actually present across diverse, under-represented populations, so risk reflects local reality instead of an imported average.
If it isn't calibrated for you, it isn't really precision. It's just a guess in better packaging.
Why genetics, diagnostics, and lifestyle belong together.
Each input answers a question the others can't. On its own, any single one can mislead you. Read against each other, they start to corroborate.
Genetics / What's possible
A probabilistic map of predisposition. It opens the door and tells us where to look. But possibility isn't reality, and genetics on its own can over- or under-read your risk.
Diagnostics / What's true now
Blood and biomarker testing reveals your body's current state. It confirms what genetics predicted, or contradicts it. That's the difference between a risk you carry and a process already underway.
Lifestyle / What explains it
Environment and mental wellbeing supply the context that turns risk into outcome. They're also the levers where change is actually possible.
One input on its own is a hypothesis. Read all three against the literature and you get a conclusion you can act on.
Built with partners in genomics and systems medicine.
Our science is delivered with Precisya, our precision-health intelligence partner, and Cellestra, our consulting partner. Together they're the backbone behind accurate sequencing, diagnostics, and interpretation.
Precisya
Precision Health Intelligence partner
Cellestra
Consulting partner
The evidence, quantified.
Evidence you can act on.
When the science is grounded, the decisions get easier. See how precision health works for you, or talk to us about the evidence behind it.